It is important to understand the symptoms of other common conditions that relate to the hand and wrist, as well as carpal tunnel syndrome, to … Here’s the two conditions broken down: Carpal Tunnel Syndrome. What appears to be Carpal Tunnel Syndrome, often is something else entirely. Numbness in the hands is a shared symptom of rheumatoid arthritis and carpal tunnel, which is why one can be mistaken for the other. Another possible cause of hand pain and numbness is rheumatoid arthritis. However, just because carpal tunnel syndrome is well-known does not mean it is the only condition that causes wrist pain and numbness. Rheumatoid arthritis. Hand pain from rheumatoid arthritis tends to be different from carpal tunnel syndrome in 2 main ways: It causes pain and stiffness in the large knuckles or joints of the wrist, rather than along a nerve path. However, it’s important to realize RA can be the catalyst for carpal tunnel , meaning both conditions could be present at the same time. “Many patients experience these symptoms more at night,” Dr. King says. This can lead to numbness or tingling throughout the hand and through the thumb to ring finger. Carpal tunnel syndrome is caused when the median nerve in the wrist becomes pinched. As its name suggests, pseudogout is often mistaken … ... carpal tunnel syndrome ... (CPPD). See Cubital Tunnel Syndrome. Thoracic Outlet Syndrome – Wisdom Conveyed in the Comments Section Unknown Author* “In fact, carpal tunnel symptoms, especially in this era of computer-hunched workers, are very likely to be caused by thoracic outlet syndrome, or thoracic-scapular dysfunction. Both of these conditions are caused by sharp crystals that collect in the joints.