Arcturus Therapeutics Announces that it has Initiated Dosing of its COVID-19 STARR™ mRNA Vaccine Candidate, LUNAR-COV19 (ARCT-021) in a Phase 1/2 study President Trump said the other day that he’d leave office if he loses the vote of the Electoral College on December 14.This is not the kind of assurance presidents of the United States typically need to make, but it was noteworthy given Trump’s disgraceful conduct since losing his bid for reelection to Joe Biden on November 3.Behind in almost all the major polls, Trump stormed within a hair’s breadth in the key battlegrounds of winning reelection, and his unexpectedly robust performance helped put Republicans in a strong position for the post-Trump-presidency era. Some locals blamed the attack on Boko Haram fighters, but Bulama Bukarti, an analyst with the Tony Blair Institute, said rival group the IS-affiliated Islamic State West Africa Province (ISWAP) were more active in the area. San Diego's Arcturus Therapeutics Announces Timeline for COVID-19 Vaccine Trial "LUNAR-COV19 is a very low dose, potential single-shot (i.m. Products in development [ edit ] The company has at least 10 programs in development for novel RNA therapeutics, both wholly owned and in collaboration with other Pharmaceutical companies and Academic Labs. 13:00 Could mRNA COVID-19 vaccines be dangerous in the long-term? The California-based company's announcement came as Pfizer said its COVID-19 vaccine is more than 90% effective based on initial trial results, a major victory in the war against a virus that has killed over a million people and battered the world's economy. Copyright © 2020 Jpost Inc. All rights reserved, A third COVID-19 lockdown for Israel is unavoidable now, It's time to end the farce of this government, UN must recognize Jewish refugees from Arab countries – opinion, Naftali Bennett: From rookie to national leader. The amount of immune response a vaccine generates is called its immunogenicity. Elsewhere, Inovio Pharmaceuticals and Sorrento Therapeutics closed down 19% and 17%, respectively. The state also contended that the forensic examination contemplated by the plaintiffs threatened state election security and could compromise its contractor’s proprietary and trade secrets, and thus should not be permitted absent a more compelling showing of wrongdoing than has been made to this point. "We must define our own European interests, and this also includes common ground (with China) on foreign policy, on economic policy and digital policy and many more," she said. In 2020, destruction of the world's largest rainforest rose 9.5 per cent from a year earlier to 11,088 square kilometers (2.7 million acres) - seven times the size of London - according to data from Brazil's national space research agency Inpe. It maintained that it was another constitutional violation for Trump election observers not to be allowed in close proximity to the counting of ballots. The firm said in a statement on Monday it had struck supply deals with Israel and Singapore - where it is working on the vaccine with a university and has been conducting trials - and was urgently working to start later stage trials. They therefore challenged the state legislature’s 2019 Act 77, which permitted “no-excuse” mail-in voting. Joining me today is Arcturus Therapeutics CEO, Joe Payne, to discuss his company's Covid-19 vaccine. This was to occur on Monday (today) -- recall that Georgia will be holding a statewide run-off election for both U.S. Senate seats in just five weeks (i.e., on January 5). The company joins Inovio Pharmaceuticals, Moderna and others in working on vaccines, which if successful could take a year to reach the wider public, experts say. The official annual measure, known as PRODES, is taken by comparing satellite images from the end of July 2020 with those from the beginning of August 2019. U.S. biotech firm Arcturus Therapeutics said it expects to start distributing its COVID-19 vaccine … Within reason, it is permissible for counties to have different procedures for handling ballots, and nothing forced some counties to permit voters to cure flawed absentee ballots and others to decline to do so.Not that it mattered. Equity analysts at Laidlaw & Company attributed the weakness in Arcturus' stock to concern that the efficacy of ARCT-021 might not be as robust as other competitors, while Roth Capital Partners said its results showed a continually improving immune response. Arcturus Therapeutics is co-developing a vaccine candidate for Covid-19 in collaboration with Duke-NUS Medical School in Singapore, called ARCT-021. If Trump’s not capable of it, he should at least stop waging war on the outcome. San Diego-based Arcturus Therapeutics has received a grant of up to $10 million to develop a vaccine for the deadly strain of coronavirus known as COVID-19. One pro-government anti-jihadist militia said the assailants tied up the labourers and slit their throats. The Amazon is the world's largest rainforest and its protection is crucial to stopping catastrophic climate change because of the vast amount of carbon dioxide it absorbs. ET About Arcturus Therapeutics. A straight apples-to-apples comparison finds that 1.8 million mail-in ballots were requested in the primary and 1.5 million returned, while 3.1 million ballots were requested in the general and 2.6 million returned.Flawed and dishonest assertions like this pollute the public discourse and mislead good people who make the mistake of believing things said by the president of the United States.Elected Republicans have generally taken the attitude that the president should be able to have his day in court. The violence centred on the village of Koshobe near the Borno state capital Maiduguri, with assailants targeting farm workers harvesting rice fields. They waited for over a year, until after 2.6 million Pennsylvanians had availed themselves of the opportunity to vote by mail during a pandemic. Both firms have a buy rating on the stock. In a rather elementary error, this compares the number of mail-ballots requested in the primary to the number of ballots counted in the general. James Dixon, 28, is charged with killing Vincell Jackson, 52, who was the boyfriend of the Thanksgiving party host. Last week, she ordered a temporary stay in the certification process -- although the stay’s efficacy was debatable, since her order came after the state had certified the results (albeit before some ministerial tasks, such as the issuance of certificates to the Biden slate of electors, who will cast the commonwealth’s electoral votes).State election officials, who are Democrats, immediately appealed to the state supreme court, where their eventual victory was certain. Japanese intelligence officials told a US expert that Kim Jong Un received a trial COVID-19 vaccine from China within the last few weeks. Thousands have fled the scene of a rumbling Indonesian volcano that burst to life for the first time in several years, belching a massive column of smoke and ash, the disaster agency said. The latest annual destruction is a substantial increase from the 7,536 square kilometers that were deforested in 2018, the year before Mr Bolsonaro took office. But authorities advised residents to wear masks to protect themselves from volcanic ash spouting from the crater in East Nusa Tenggara - the southernmost province of Indonesia - and to be alert for possible lava flows. Indeed, some of the plaintiffs had run for office under the Act 77 mail-in procedures without objecting to them.Consequently, the court ruled that the doctrine of laches applied -- i.e., claims must be timely raised or they are forfeited. Sign up now!Daily Beast Membership: Beast Inside goes deeper on the stories that matter to you. In the meantime, the state is to provide the plaintiffs with a copy of its contract with Dominion, and must file by close of business Wednesday (December 2) a brief and any supporting affidavits in opposition to the forensic examinations.Another hearing in the case is set for Friday (December 4). Two judges dissented in part, reasoning that the Republican plaintiffs’ construction of the state constitution appears sound, and that Act 77’s attempt to put a 180-day time-limit on challenges to its lawfulness should be unenforceable against challenges based on the state constitution (an issue the majority opinion sidestepped). On Sunday, they won a minor victory -- on procedural grounds, not on the merits -- in their bid to convince a Georgia federal judge to decertify the GOP-controlled state government’s conclusion that President-elect Biden won a slim victory there.PennsylvaniaThe state lawsuit in Pittsburgh was brought by U.S. Representative Mike Kelly of northwestern Pennsylvania and other Republicans. The injunction freezes matters for a few days so the court can consider the parties’ positions and make a more informed decision. An opinion piece published Sunday by a hard-line Iranian newspaper urged Iran to attack the Israeli port city of Haifa if Israel carried out the killing of the scientist who founded the Islamic Republic’s military nuclear program in the early 2000s. Georgia officials responded to a barrage of attacks by President Trump by saying they would continue to “follow the law” on counting votes and certifying the election results, which show a narrow win by President-elect Joe Biden. Along with Nike and Coca-Cola, tech giant Apple is also pushing to weaken some restrictions, the Washington Post reported last week.Coca-Cola "strictly prohibits any type of forced labor in our supply chain" and employs third-party auditors to enforce the policy, the company said in a statement to the Times. The author of the article, Dmitry Steshin, urged, “Beat the whites until they turn Black.” Simonyan shared the article, describing it as a piece of “good advice from an international journalist to the negroes of Minnesota and the United States.”Simonyan’s husband followed up the obscene sketch on his program with a ludicrous assertion: “There is no racism in Russia.” It was no more believable than the notorious Soviet claim, “There is no sex in the USSR.”Read more at The Daily Beast.Get our top stories in your inbox every day. Neither the president's statement nor Sunday's from the UN mentioned either Boko Haram or rival group ISWAP by name. Act 77 marked a departure from prior Pennsylvania law, under which voters could only request absentee ballots based on legally approved reasons for not being able to vote in person. The attack, in a state gripped by a jihadist insurgency for more than 10 years, took place the same day as long-delayed local elections in the state. The apparent success for BNT162b2 could bode well for Arcturus' COVID-19 vaccine candidate. In a statement, he noted that the disease "affects people differently" and "more than a thousand Americans are dying every day and many more are hospitalized." There was zero chance that it would side with Republicans.Here, however, the court was on solid footing because the plaintiffs did not file lawsuits against the new mail-in voting when it was enacted. Kallon, in his statement, said: "The incident is the most violent direct attack against innocent civilians this year. U.S. biotech firm Arcturus Therapeutics said it expects to start distributing its COVID-19 vaccine candidate in the first quarter of next year after early stage trials showed promising results. The … Arcturus’ diverse pipeline of RNA therapeutic and vaccine candidates includes self-replicating mRNA vaccine programs for SARS-CoV-2 (COVID-19) and Influenza, and other programs to … The sketch concluded with a recommendation that rather than read Obama’s book, The Audacity of Hope, viewers should opt for “reading the label on the bathroom air freshener.”Facing worldwide condemnation for the latest racist episode, Margarita Simonyan—heralded as one of the most influential women in news media—attempted to backpedal, using her husband’s Armenian ethnicity as some kind of an excuse for his indefensible racism. This anticipation revived the wave of racist attacks against former President Barack Obama, which were commonplace during his administration.Overt racism in Russian state media is far from uncommon but nonetheless continues to be shocking. Equity analysts at Laidlaw & Company attributed the weakness in Arcturus' stock to concern that the efficacy of ARCT-021 might not be as robust as other competitors, while Roth Capital Partners said its results showed a continually improving immune response. Arcturus Therapeutics, a leading messenger RNA medicines company focused on the discovery, development and commercialization of therapeutics for rare diseases and vaccines, announced plans to initiate a human clinical trial this Summer for its COVID-19 vaccine… SAN DIEGO and SINGAPORE, March 04, 2020 (GLOBE NEWSWIRE) -- Arcturus Therapeutics (the “Company”, NASDAQ: ARCT), a leading messenger RNA medicines company, and Duke-NUS Medical School (Duke-NUS), a research intensive, graduate entry medical school, today announced their partnership to develop a Coronavirus (COVID-19) vaccine for Singapore. President-elect Joe Biden will likely wear a walking boot for the next several weeks as he recovers from breaking his right foot while playing with one of his dogs, his doctor said. Arcturus also has a candidate for a Covid-19 vaccine. Although the Constitution empowers the state legislature to choose the manner of selecting electors, Judge Wecht observed (as I have also pointed out) that the commonwealth’s legislature did so long ago by enacting provisions that award Pennsylvania’s Electoral College votes to the winner of the popular election.The court’s ruling on the issue of laches was unanimous. What America has long expected is that losing candidates swallow those feelings and at least pretend to be gracious. Kallon, citing "reports that several women may have been kidnapped", called for their immediate release. "More stories from theweek.com Americans are choosing death over deprivation How camp explains Trump The case for shortening the presidential transition. Fax: 972-3-561-3699 Tim O'Donnell> Grassley, 87, is back at the Senate today after testing positive for Covid-19. (Reporting by John Geddie; Editing by Jacqueline Wong and Richard Pullin). The victims included dozens of labourers from Sokoto state in northwestern Nigeria, roughly 1,000 kilometres (600 miles) away, who had travelled to the northeast to find work, it said. Differentiated STARR™ mRNA vaccine expected to produce humoral and cellular immunity at very low doses. Sen. Chuck Grassley (R-Iowa) has returned to his Washington office two weeks after he tested positive for COVID-19, his team announced Monday.While Grassley wasn't the first lawmaker to contract the virus, many people were concerned about the diagnosis because the senator is 87. SINGAPORE — U.S. biotech firm Arcturus Therapeutics said it expects to start distributing its COVID-19 vaccine candidate in the first quarter of next year after early stage trials showed promising results. district judge Timothy Batten initially issued a temporary injunction, directing state election officials to preserve the machines in their present condition while he deliberated over whether to permit a forensic examination. US biotech firm Arcturus Therapeutics said it expects to start distributing its COVID-19 vaccine candidate in the first quarter of next year after early stage trials showed promising results. Multinational corporations including Nike and Coca-Cola are lobbying to water down legislation that would ban products made with forced labor in China's Xinjiang province, the New York Times reported on Sunday.China has attempted to cement state power over millions of Muslim citizens in Xinjiang, mostly Uyghur Muslims along with Kazakhs and other minorities. How Many Really Mean It? Krebs explained on Sunday's 60 Minutes why he's so sure the election was free from hacking and foreign meddling, and why Trump and his fringy lawyers are wrong to allege otherwise. Moreover, to repeat a refrain we’ve been stressing for a while, there was a gross mismatch between the harm alleged and the remedy sought: The Republicans were asking that the mail-in ballots be thrown out or, in the alternative, that the election be voided and the (Republican-majority) state legislature be directed to choose the state’s electors (i.e., the Trump slate). The court pointed out that the suit challenged the procedures to fix absentee ballots in seven Democratic counties, which don’t even come close to having enough cured ballots to change the outcome in the state; the counties might have allowed, at most, 10,000 voters to fix their ballots, and even if every single one of them voted for Biden, that’s still far short of Biden’s 80,000-plus margin in the state.The idea, as the Trump team stalwartly maintains, that the Supreme Court is going to take up this case and issue a game-changing ruling is fantastical. But the president can’t stand to admit that he lost and so has insisted since the wee hours of Election Night that he really won -- and won “by a lot.”There are legitimate issues to consider after the 2020 vote about the security of mail-in ballots and the process of counting votes (some jurisdictions, bizarrely, take weeks to complete their initial count), but make no mistake: The chief driver of the post-election contention of the past several weeks is the petulant refusal of one man to accept the verdict of the American people. The dissenters argued that the plaintiffs should be permitted to proceed with their objections to mass mail-in voting for the purpose of future elections, but not the 2020 election.GeorgiaIn Georgia, attorneys Lin Wood and Sidney Powell are pursuing their theory that the election was stolen from President Trump by cyber-fraud -- specifically, manipulation of the tabulation program, to which they claim Dominion voting machines are vulnerable, in order to switch Trump votes to Biden votes.Sunday turned out to be a frenetic day because Wood learned, apparently from state election officials, that the memories on voting machines were about to be reset (or “wiped,” as Wood put it). An Oregon cancer nurse was put on leave after boasting on TikTok about ignoring COVID-19 rules, Trump lashes out at 60 Minutes in furious tweets over interview with fired elections official, Ex-U.S. cybersecurity chief Chris Krebs tells 60 Minutes how he knows the 2020 election wasn't rigged, Georgia governor, defying Trump, says he'll 'follow the law' on election results, Kremlin-Funded TV Airs Mind-Numbingly Racist Blackface Attack on Obama, Lối đi mới thoát "dốt" tiếng Anh cho người mất gốc, Chuck Grassley returns to Senate after COVID-19 infection, calls for 'long overdue relief legislation', More than 100 civilians dead in 'gruesome' Nigeria attack blamed on Islamic jihadists, Iran newspaper: Strike Haifa if Israel killed scientist, Nike, Coca-Cola, Apple among Companies Lobbying against Uyghur Forced Labor Bill, North Korean leader Kim Jong Un may have already received an unapproved coronavirus vaccine, In ancient Italian monastery, monks defend a 1,600-year-old dying tradition, Brazil Amazon deforestation rises to highest level in over a decade, Biden breaks foot while playing with dog, to wear a boot, Merkel: Challenge with China is finding right balance between values and interests, 'I don't see any way around it': Former Navy SEAL McRaven says retaliation for assassination of top Iranian nuclear scientist all but certain, Trump Campaign Election Litigation Appears to End in Pennsylvania While Proceeding in Georgia, Thousands flee as Indonesian volcano bursts to life, Man slain in Chicago dispute over hands in Thanksgiving food, Charles Manson follower has parole blocked by California governor, Switzerland halves new infections without national lockdown as pubs and restaurants stay open, Over 300 detained in Belarus during anti-government protests. "The Iranians are going to be in a position where they have to retaliate. ), self-replicating mRNA vaccine … While environmentalists blamed the government for the rise, federal officials hailed the figures as a sign of progress in fighting deforestation, as the increase was far lower than the 34 per cent increase recorded in 2019. ... State and local election officials did the right thing. Too little immunogenicity and the vaccine is ineffective. She described the offensive sketch as a “parody of Obama” and disingenuously claimed, “As someone who is part of an ethnic minority in Russia, Tigran regularly makes fun, on the air, of his large 'ethnic' nose and his belonging to a 'Black' community (look it up if you don't know which ethnicities are referred to as 'Black' in Russia).”Despite Simonyan’s clumsy excuses, her husband is not the only one who considers himself somehow entitled to mock Black Americans. Judge Batten withdrew the injunction a few hours later when the state officials named in the Wood/Powell lawsuits explained that the counties, not the state, had control over the machines.Finally, on Sunday evening at 7:45 p.m., Batten convened an emergency conference, via Zoom, at which the lawyers countered that they were prepared to amend their complaints in order to add the officials in Cobb, Gwinnett, and Cherokee county as defendants. Wood and Powell replied that these concerns could be assuaged by allowing the state’s own experts to participate in the examination, conducting it on videotape, and directing that the results be provided only to the court, for consideration of any appropriate protective orders against disclosure.At the conclusion of the hearing, Judge Batten issued a temporary restraining order: For the next ten days, unless the court directs otherwise, Georgia is barred from permitting the erasure or alteration of data from the Dominion machines.