It also is given intravenously at similar daily dosages. It also has been used for cancer, liver ailments, and various other conditions. Dosing. Objective: Alpha-lipoic acid is a natural molecule, which directly or by means of its reduced form, dihydrolipoic acid, exerts antioxidant, anti-inflammatory and immunomodulatory activities, very helpful also in preventing miscarriage and preterm delivery. Alpha-lipoic acid (ALA) has been used as an antioxidant for the treatment of diabetes and HIV. Used as dietary supplement alpha-lipoic acid was demonstrated to be safe for living organisms even when administered at high doses. Oral dosage of alpha-lipoic acid given in numerous clinical studies ranges from 200 to 1,800 mg daily.